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Antxr1tm1.1Bstc
Targeted Allele Detail
Summary
Symbol: Antxr1tm1.1Bstc
Name: anthrax toxin receptor 1; targeted mutation 1.1, Brad St Croix
MGI ID: MGI:4353382
Synonyms: TEM8neo
Gene: Antxr1  Location: Chr6:87110835-87312757 bp, - strand  Genetic Position: Chr6, 37.94 cM
Alliance: Antxr1tm1.1Bstc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:150947
Parent Cell Line:  v6.4 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 1 and an frt and loxP flanked neo cassette was inserted downstream of exon 1. Flp mediated recombination removed the neo cassette leaving exon 1 floxed. (J:150947)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Antxr1 Mutation:  29 strains or lines available
References
Original:  J:150947 Cullen M, et al., Host-derived tumor endothelial marker 8 promotes the growth of melanoma. Cancer Res. 2009 Aug 1;69(15):6021-6
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory