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Antxr1tm1Lepp
Targeted Allele Detail
Summary
Symbol: Antxr1tm1Lepp
Name: anthrax toxin receptor 1; targeted mutation 1, Stephen H Leppla
MGI ID: MGI:4352939
Synonyms: TEM8flp
Gene: Antxr1  Location: Chr6:87110835-87312757 bp, - strand  Genetic Position: Chr6, 37.94 cM
Alliance: Antxr1tm1Lepp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:150952
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 13, which encodes the transmembrane domain, and an frt flanked neo cassette and second loxP site were inserted downstream of exon 13. (J:150952)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Antxr1 Mutation:  29 strains or lines available
References
Original:  J:150952 Liu S, et al., Capillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12424-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory