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Tg(Foxl1-cre)1Khk
Transgene Detail
Summary
Symbol: Tg(Foxl1-cre)1Khk
Name: transgene insertion 1, Klaus H Kaestner
MGI ID: MGI:3769667
Synonyms: Foxl1-Cre
Transgene: Tg(Foxl1-cre)1Khk  Location: unknown  
Alliance: Tg(Foxl1-cre)1Khk page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Foxl1-cre)1Khk expression driven by 1 gene
 
Mutation detailsUsing BAC RP23-446J14, the researchers replaced the Foxl1 open reading frame with an IRES-cre cassette and the Foxc2 gene with an frt-flanked kanamycin cassette to prevent any expression from it. The kanamycin was later removed by flp-mediated recombination. Cre is expressed in the mesenchymal cells of the stomach and intestines. (J:128623)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Foxl1 (mouse)
Summary of all recombinase alleles driven by Foxl1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:128623 Sackett SD, et al., Foxl1-Cre BAC transgenic mice: a new tool for gene ablation in the gastrointestinal mesenchyme. Genesis. 2007 Aug;45(8):518-22
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory