Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Glultm1Whla
Name:	glutamate-ammonia ligase; targeted mutation 1, Wouter H Lamers
MGI ID:	MGI:3715484
Synonyms:	GSLacZ
Gene:	Glul  Location: Chr1:153775692-153785469 bp, + strand  Genetic Position: Chr1, 65.43 cM, cytoband G2
Alliance:	Glultm1Whla page

Germline Transmission:	Earliest citation of germline transmission: J:122377
Parent Cell Line:	IB10/E14IB10 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 through 7 are replaced with a lacZ-neo cassette to create a null allele. RT-PCR was used to confirm the altered transcript. (J:122377)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	11 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Glul Mutation:	33 strains or lines available

Original:	J:122377 He Y, et al., Glutamine synthetase is essential in early mouse embryogenesis. Dev Dyn. 2007 Jul;236(7):1865-75
All:	4 reference(s)