Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Rims2tm1Schc
Name:	regulating synaptic membrane exocytosis 2; targeted mutation 1, Susanne Schoch
MGI ID:	MGI:3706334
Gene:	Rims2  Location: Chr15:39061681-39547768 bp, + strand  Genetic Position: Chr15, 15.45 cM, cytoband C
Alliance:	Rims2tm1Schc page

Germline Transmission:	Earliest citation of germline transmission: J:119934
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     Exon 5 was flanked with loxP sites. An frt-flanked neo was included in the vector. (J:119934)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rims2 Mutation:	250 strains or lines available

Original:	J:119934 Schoch S, et al., Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release. EMBO J. 2006 Dec 13;25(24):5852-63
All:	1 reference(s)