Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Otx2tm1.1Tlam
Name:	orthodenticle homeobox 2; targeted mutation 1.1, Thomas Lamonerie
MGI ID:	MGI:3695699
Synonyms:	Otx2flox
Gene:	Otx2  Location: Chr14:48894238-48905101 bp, - strand  Genetic Position: Chr14, 25.36 cM
Alliance:	Otx2tm1.1Tlam page

Germline Transmission:	Earliest citation of germline transmission: J:116888
Parent Cell Line:	ENS (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     LoxP sites were inserted to flank exon 2. (J:116888)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Otx2 Mutation:	50 strains or lines available

Original:	J:116888 Fossat N, et al., Temporal and spatial delineation of mouse Otx2 functions by conditional self-knockout. EMBO Rep. 2006 Aug;7(8):824-30
All:	12 reference(s)