Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Il4tm1(CD2)Mmrs
Name:	interleukin 4; targeted mutation 1, Markus Mohrs
MGI ID:	MGI:3686902
Synonyms:	IL4KN2, KN2
Gene:	Il4  Location: Chr11:53503287-53509492 bp, - strand  Genetic Position: Chr11, 31.97 cM
Alliance:	Il4tm1(CD2)Mmrs page

Germline Transmission:	Earliest citation of germline transmission: J:113279
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted Mutation:    Insertion     The first two exons were replaced with human CD2. (J:113279)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il4 Mutation:	42 strains or lines available

Original:	J:113279 Mohrs K, et al., A two-step process for cytokine production revealed by IL-4 dual-reporter mice. Immunity. 2005 Oct;23(4):419-29
All:	37 reference(s)