Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Igktm1Rsky
Name:	immunoglobulin kappa chain complex; targeted mutation 1, Klaus Rajewsky
MGI ID:	MGI:3662618
Synonyms:	3-83kappai, Igktm1Pld
Gene:	Igk  Location: Chr6:67532620-70703738 bp, + strand  Genetic Position: Chr6, 30.89 cM, cytoband F1-pter

Germline Transmission:	Earliest citation of germline transmission: J:35357
Parent Cell Line:	E14.1TG3B1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Inserted expressed sequence) Mutations:    Insertion, Intergenic deletion   Mutation details: A targeting vector was used to insert a floxed neo (subsequently removed via cre mediated recombination) and a recombined Vk3-83-Jk2 region replacing J1 and J2. (J:35357)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Igk Mutation:	25 strains or lines available

Original:	J:35357 Pelanda R, et al., A prematurely expressed Ig kappa transgene, but not a V kappa J kappa gene segment targeted into the Ig kappa locus, can rescue B cell development in lambda 5-deficient mice. Immunity. 1996 SEP;5(3):229-239
All:	22 reference(s)