Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Atp2b2m1Mae
Name:	ATPase, Ca++ transporting, plasma membrane 2; mutation 1, Nobuyo Maeda
MGI ID:	MGI:3641249
Synonyms:	T692K
Gene:	Atp2b2  Location: Chr6:113720803-114019574 bp, - strand  Genetic Position: Chr6, 52.85 cM
Alliance:	Atp2b2m1Mae page

Germline Transmission:	Earliest citation of germline transmission: J:110607
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Spontaneous (Null/knockout) Mutation:    Single point mutation   Mutation details: A C to A transversion is located at nucleotide 2075 in exon 13 resulting in a Thr to Lys substitution at position 629. This mutation was found in YTC-1 cells used to generate a line of Ppargtm2Mae mice, but not in YTC-2 cells used to generate a second line of the same targeted mutation. (J:110607)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atp2b2 Mutation:	66 strains or lines available

Original:	J:110607 Tsai YS, et al., A de novo deafwaddler mutation of Pmca2 arising in ES cells and hitchhiking with a targeted modification of the Pparg gene. Mamm Genome. 2006 Jul;17(7):716-22
All:	1 reference(s)