Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Htr1ftm1Dgen
Name:	5-hydroxytryptamine (serotonin) receptor 1F; targeted mutation 1, Deltagen
MGI ID:	MGI:3604523
Gene:	Htr1f  Location: Chr16:64745092-64926147 bp, - strand  Genetic Position: Chr16, 37.1 cM
Alliance:	Htr1ftm1Dgen page

Germline Transmission:	Earliest citation of germline transmission: J:101679
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd
Project Collection:	Deltagen

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. Low levels of RNA transcripts are detectable in brain, cortex, subcortical region, brainstem, olfactory bulb, large intestine, cecum and testis. No RNA transcripts are detectable in cerebellum, spinal cord, eye, Harderian glands, heart, lung, liver, pancreas, kidney, spleen, thymus, lymph nodes, bone marrow, skin, gallbladder, urinary bladder, pituitary gland, adrenal gland, salivary gland, skeletal muscle, tongue, stomach, small intestine, epididymis, seminal vesicle, coagulating gland, prostate gland, ovaries, uterus and white fat. LacZ (beta-galactosidase) expression is detectable in brain, spinal cord, pituitary gland and testis. Most striking expression is observed in brain.

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

61 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Htr1f Mutation:	28 strains or lines available

Original:	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:	1 reference(s)