Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Adcy7tm1Dgen
Name:	adenylate cyclase 7; targeted mutation 1, Deltagen
MGI ID:	MGI:3604498
Gene:	Adcy7  Location: Chr8:88999031-89056590 bp, + strand  Genetic Position: Chr8, 43.06 cM
Alliance:	Adcy7tm1Dgen page

Mutant Cell Line:	4302
Germline Transmission:	Earliest citation of germline transmission: J:101679
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd
Project Collection:	Deltagen

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. The highest levels of RNA transcripts are detectable in lymph nodes and adrenal gland. Moderate levels of RNA transcripts are detectable in lung, spleen, thymus, skin, gallbladder, urinary bladder, pituitary gland, testis, epididymis, prostate gland, ovary, uterus and white fat. LacZ expression was detected in: brain, thymus, spleen, lymph nodes, bone marrow, aorta, heart, lung, pancreas, kidney, urinary bladder, thyroid gland, skeletal muscle, skin, testis, prostate gland, ovary and uterus.

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

30 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adcy7 Mutation:	59 strains or lines available

Original:	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:	2 reference(s)