Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bmpr2tm1.2Enl
Name:	bone morphogenetic protein receptor type 2; targeted mutation 1.2, En Li
MGI ID:	MGI:3574813
Synonyms:	BMPR-II1loxP
Gene:	Bmpr2  Location: Chr1:59802721-59917240 bp, + strand  Genetic Position: Chr1, 30.44 cM, cytoband C2
Alliance:	Bmpr2tm1.2Enl page

Germline Transmission:	Earliest citation of germline transmission: J:97109
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Bmpr2tm1.1Enl were crossed with EIIa-cre mice to remove exons 4 and 5. This deletion created a frame shift in exon 6, with the first stop codon following 11 missense amino acids. (J:97109)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bmpr2 Mutation:	45 strains or lines available

Original:	J:97109 Beppu H, et al., Generation of a floxed allele of the mouse BMP type II receptor gene. Genesis. 2005 Mar;41(3):133-7
All:	4 reference(s)