Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Chd7Cycn
Name:	chromodomain helicase DNA binding protein 7; cyclone
MGI ID:	MGI:1862039
Synonyms:	Cyc, Gena52, GENA 52
Gene:	Chd7  Location: Chr4:8690406-8867659 bp, + strand  Genetic Position: Chr4, 3.68 cM
Alliance:	Chd7Cycn page

Strain of Origin:

BALB/cOlaHsd

Allele Type:    Chemically induced (ENU) Mutation:    Nucleotide substitutions   Mutation details: A T4286A transition in exon 18 resulted in an L1429X nonsense mutation. This mutation putatively results in a protein lacking only the most C-terminal NLS, SANT, and BRK domains. (J:104123) Inheritance:    Dominant

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Chd7 Mutation:	136 strains or lines available

Original:	J:63816 Nolan PM, et al., A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet. 2000 Aug;25(4):440-3
All:	3 reference(s)