Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Lyz2tm1Graf
Name:	lysozyme 2; targeted mutation 1, Thomas Graf
MGI ID:	MGI:2654929
Synonyms:	LysEGFP, lys-EGFP-ki
Gene:	Lyz2  Location: Chr10:117113446-117118177 bp, - strand  Genetic Position: Chr10, 65.34 cM
Alliance:	Lyz2tm1Graf page

Germline Transmission:	Earliest citation of germline transmission: J:63254
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: The gene was disrupted by insertion of EGFP and floxed neomycin resistance cassettes directly downstream of the translation initiation codon via homologous recombination. (J:63254)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lyz2 Mutation:	41 strains or lines available

Original:	J:63254 Faust N, et al., Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages. Blood. 2000 Jul 15;96(2):719-26
All:	15 reference(s)