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Phenotypes Associated with This Genotype
Genotype
MGI:8407107
Allelic
Composition		 Sftpctm1Mfbs/Sftpc+
Gt(ROSA)26Sortm3(CAG-flpo/ERT2)Alj/Gt(ROSA)26Sor+
Genetic
Background		 B6.Cg-Gt(ROSA)26Sortm3(CAG-flpo/ERT2)Alj Sftpctm1Mfbs
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm3(CAG-flpo/ERT2)Alj mutation (2 available); any Gt(ROSA)26Sor mutation (1243 available)
Sftpctm1Mfbs mutation (0 available); any Sftpc mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
alveolitis ( J:267027 )
• adult mice administered intraperitoneal tamoxifen develop moderate alveolitis and interstitial histological changes 2 weeks after induction

immune system
alveolitis ( J:267027 )
• adult mice administered intraperitoneal tamoxifen develop moderate alveolitis and interstitial histological changes 2 weeks after induction

mortality/aging
mortality/aging ( J:267027 )
N
• tamoxifen-treated mice do not show early mortality

growth/size/body
growth/size/body region phenotype ( J:267027 )
N
• tamoxifen-treated mice do not show weight loss

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/06/2026
MGI 6.29 		The Jackson Laboratory