Phenotypes for Fgfr3 Gt(ROSA)26Sor Tg(Col11a2-cre/ERT)#Ntsu MGI:8404486 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Fgfr3^em1.1Ntsu/Fgfr3⁺ Gt(ROSA)26Sor^{tm1(CAG-Brainbow2.1)Cle}/Gt(ROSA)26Sor⁺ Tg(Col11a2-cre/ERT)#Ntsu/0
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JJcl * C57BL/6NSlc

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgfr3^em1.1Ntsu mutation (0 available); any Fgfr3 mutation (54 available)
Gt(ROSA)26Sor^{tm1(CAG-Brainbow2.1)Cle} mutation (3 available); any Gt(ROSA)26Sor mutation (1243 available)
Tg(Col11a2-cre/ERT)#Ntsu mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal long bone epiphyseal plate morphology ( J:390604 )

• mice administered tamoxifen at P20 show more variable angles of chondrocyte clonal cell stacks relative to the longitudinal axis of the growth plate cartilage suggesting that clonal progeny cells move in random directions and remain within the resting zone and do not move into the proliferative zone

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/06/2026 MGI 6.29