Phenotypes Associated with This Genotype

Genotype
MGI:7751184

• Allelic Composition: Gt(ROSA)26Sor^{em5(CAG-KANK4,-tdTomato)Bcgen}/Gt(ROSA)26Sor⁺; Tg(Cdh5-cre/ERT2)1Rha/0
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal artery morphology ( J:326312 )

♂ • diameter of collateral arteries of ischemic hindlimbs is increased in tamoxifen-treated mice

decreased capillary density ( J:326312 )

♂ • the capillary density in the gastrocnemius muscles of ischemic hindlimbs is decreased in tamoxifen-treated mice

abnormal vascular development ( J:326312 )

♂ • tamoxifen-treated mice show increased collateral artery arteriogenesis in the hindlimb ischemia model

abnormal blood circulation ( J:326312 )

♂ • tamoxifen-treated mice show increased blood perfusion in the ischemic hindlimbs 21 days after femoral artery ligation