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Phenotypes Associated with This Genotype
Genotype
MGI:7625703
Allelic
Composition		 Cd79atm1(cre)Reth/Cd79a+
Orai3em1.1Treb/Orai3em1.1Treb
Genetic
Background		 involves: BALB/c * C57BL/6J * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd79atm1(cre)Reth mutation (3 available); any Cd79a mutation (26 available)
Orai3em1.1Treb mutation (0 available); any Orai3 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:345485 )
N
• store-operated Ca2+ entry in B cells is not significantly different from controls
abnormal B cell activation ( J:345485 )
• anti-IgM stimulated proliferation is similar to control but viability is increased

hematopoietic system
abnormal B cell activation ( J:345485 )
• anti-IgM stimulated proliferation is similar to control but viability is increased

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory