Phenotypes Associated with This Genotype

Genotype
MGI:7614873

• Allelic Composition: Alpk1^em1Dlka/Alpk1^em1Dlka; Crb1^rd8/Crb1^rd8
• Genetic Background: involves: C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

growth/size/body region phenotype ( J:344848 )

N • normal body and spleen weight at age 6, 12 and 16 weeks

homeostasis/metabolism

abnormal circulating chemokine level ( J:344848 )

• increased serum CXCL1 and CCL2 levels at age 2 and 3 months

increased circulating CXCL10 level ( J:344848 )

• increased serum CXCL10 levels at age 2 and 3 months

immune system

immune system phenotype ( J:344848 )

N • normal spleen weight at age 6, 12 and 16 weeks

abnormal circulating chemokine level ( J:344848 )

• increased serum CXCL1 and CCL2 levels at age 2 and 3 months

increased circulating CXCL10 level ( J:344848 )

• increased serum CXCL10 levels at age 2 and 3 months