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Phenotypes Associated with This Genotype
Genotype
MGI:7611733
Allelic
Composition		 Cd79atm1(cre)Reth/Cd79a+
Phf5atm1.1Oux/Phf5atm1.1Oux
Tg(IghelMD4)4Ccg/0
Genetic
Background		 involves: BALB/c * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd79atm1(cre)Reth mutation (3 available); any Cd79a mutation (26 available)
Phf5atm1.1Oux mutation (0 available); any Phf5a mutation (17 available)
Tg(IghelMD4)4Ccg mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal B cell number ( J:345807 )
• addition of a pre-rearranged IgH transgene partially but significantly increases the number of CD19+ B cells

immune system
abnormal B cell number ( J:345807 )
• addition of a pre-rearranged IgH transgene partially but significantly increases the number of CD19+ B cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory