Phenotypes for a Ces1c MGI:7596325 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	a/a Ces1c^e/Ces1c^e
Genetic Background	B6;D2-a Ces1c^e/EiJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (166 available); any a mutation (468 available)
Ces1c^e mutation (2 available); any Ces1c mutation (38 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

abnormal enzyme/coenzyme activity ( J:345412 )

• 3-fold decreased in total plasma esterases activity compared with B6D2F1

abnormal xenobiotic metabolism ( J:345412 )

• 200-fold reduction in SN-38 production after incubation with CPT-11 in vitro

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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