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Phenotypes Associated with This Genotype
Genotype
MGI:7580561
Allelic
Composition		 Rr79em2Rtew/Rr79em2Rtew
Tg(TcraTcrb)1100Mjb/?
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr79em2Rtew mutation (1 available); any Rr79 mutation (1 available)
Tg(TcraTcrb)1100Mjb mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal T cell activation ( J:332957 )
• reduced T cell expansion in response to antigen with a higher percentage of terminal effector CD8 cells and lower development of memory T cells

immune system
abnormal T cell activation ( J:332957 )
• reduced T cell expansion in response to antigen with a higher percentage of terminal effector CD8 cells and lower development of memory T cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory