Phenotypes for Casp8 Ripk1 Ripk3 MGI:7573096 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Casp8^em1Hbz/Casp8^em1Hbz Ripk1^em4Hbz/Ripk1^em4Hbz Ripk3^tm1Xidw/Ripk3^tm1Xidw
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Casp8^em1Hbz mutation (0 available); any Casp8 mutation (45 available)
Ripk1^em4Hbz mutation (0 available); any Ripk1 mutation (32 available)
Ripk3^tm1Xidw mutation (0 available); any Ripk3 mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body size ( J:342732 )

integument

scaly skin ( J:342732 )

skin lesions ( J:342732 )

• focal cutaneous lesions

mortality/aging

preweaning lethality, complete penetrance ( J:342732 )

• mice die by age P14

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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