Phenotypes Associated with This Genotype

Genotype
MGI:7543774

• Allelic Composition: Bicra^em3Hzhg/Bicra^em3Hzhg; H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
• Genetic Background: involves: C57BL/6J * CBA/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:335098 )

neonatal lethality, incomplete penetrance ( J:335098 )

cardiovascular system

abnormal heart morphology ( J:335098 )

• at P0

double outlet right ventricle ( J:335098 )

• at E15 and E16.5 without abnormal thickness of the ventricular wall and ventricular septum

ventricular septal defect ( J:335098 )

• at E15 and E16.5 without abnormal thickness of the ventricular wall and ventricular septum

decreased cardiac output ( J:335098 )

• lower right ventricular output

abnormal coronary circulation ( J:335098 )

• transventricular septal flow

decreased heart right ventricle muscle contractility ( J:335098 )

• reduced right ventricular output stroke volume and ejection fraction

growth/size/body

decreased body size ( J:335098 )

• at P7

muscle

decreased heart right ventricle muscle contractility ( J:335098 )

• reduced right ventricular output stroke volume and ejection fraction