Phenotypes for App Mapt Prnp MGI:7520916 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	App^tm3.1Tcs/App^tm3.1Tcs Mapt^{tm1.1(MAPT)Tcs}/Mapt^{tm1.1(MAPT)Tcs} Prnp^tm2Edin/Prnp^tm2Edin
Genetic Background	B6.Cg-Prnp^tm2Edin Mapt^{tm1.1(MAPT)Tcs} App^tm3.1Tcs

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
App^tm3.1Tcs mutation (2 available); any App mutation (118 available)
Mapt^{tm1.1(MAPT)Tcs} mutation (4 available); any Mapt mutation (453 available)
Prnp^tm2Edin mutation (7 available); any Prnp mutation (143 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24