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Phenotypes Associated with This Genotype
Genotype
MGI:7496048
Allelic
Composition
Del(7Saa1-Saa2)1Itl/Del(7Saa1-Saa2)1Itl
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7Saa1-Saa2)1Itl mutation (2 available); any Del(7Saa1-Saa2)1Itl mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• following LPS treatment
• the increased size of acute-phase HDL in LPS-treated mice is associated with an increased content of surface lipids, particularly phospholipids but not surface proteins, compared with similarly treated wild-type mice
• in male mice treated with LPS unlike similarly treated wild-type male mice
• however, female mice exhibit a normal increase in serum cholesterol levels following LPS treatment


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory