Analysis Tools
cardiovascular system
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• increased incidence of heart defects compared to mice heterozygous for the Nipbl allele alone (83% compared to 30%)
• spectrum of defects is more varied in type and more severe than in mice heterozygous for the Nipbl allele alone
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• in 2 heartts
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• sometimes seen in combination with ventricular septal defects
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• sometimes seen in combination with atrial septal defects
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