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Phenotypes Associated with This Genotype
Genotype
MGI:7492228
Allelic
Composition		 NipblGt(EUCE313f02)1.1Hmgu/Nipbl+
Sox17tm2.1(icre)Heli/Sox17+
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)1.1Hmgu mutation (0 available); any Nipbl mutation (125 available)
Sox17tm2.1(icre)Heli mutation (0 available); any Sox17 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:236978 )
• heart size is similar to wild-type
atrial septal defect ( J:236978 )
• in 26% of hearts at E17.5

growth/size/body
growth/size/body region phenotype ( J:236978 )
• body size is similar to wild-type

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory