Phenotypes Associated with This Genotype

Genotype
MGI:7492170

• Allelic Composition: Nipbl^{Gt(EUCE313f02)Hmgu}/Nipbl⁺
• Genetic Background: involves: 129P2/OlaHsd * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:236978 )

• only 4% of pups survive to weaning

cardiovascular system

ostium secundum atrial septal defect ( J:236978 )

• at E17.5 in about 30% of mice

• however, no ventricular septal defect, arterial stenosis or obvious abnormalities of ventricular wall thickness are seen

small heart ( J:236978 )

• in proportion to decrease in body size

growth/size/body

decreased body size ( J:236978 )