Phenotypes Associated with This Genotype

Genotype
MGI:7471941

• Allelic Composition: Clock^{em1(IMPC)Ccpcz}/Clock^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Clock^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Clock

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

decreased heart rate ( J:211773 )

♀

IMPC - CCP-IMG

craniofacial

abnormal tooth morphology ( J:211773 )

♂

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

growth/size/body

abnormal tooth morphology ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

decreased red blood cell distribution width ( J:211773 )

♂

IMPC - CCP-IMG

decreased CD8-positive, naive alpha-beta T cell number ( J:211773 )

♂

IMPC - CCP-IMG

decreased effector memory T-helper cell number ( J:211773 )

IMPC - CCP-IMG

increased leukocyte cell number ( J:211773 )

♂

IMPC - CCP-IMG

increased eosinophil cell number ( J:211773 )

♂

IMPC - CCP-IMG

increased lymphocyte cell number ( J:211773 )

♂

IMPC - CCP-IMG

increased CD4-positive, alpha-beta T cell number ( J:211773 )

IMPC - CCP-IMG

increased T-helper cell number ( J:211773 )

IMPC - CCP-IMG

decreased spleen weight ( J:211773 )

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - CCP-IMG

increased circulating triglyceride level ( J:211773 )

♂

IMPC - CCP-IMG

decreased circulating calcium level ( J:211773 )

♀

IMPC - CCP-IMG

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - CCP-IMG

decreased circulating serum albumin level ( J:211773 )

IMPC - CCP-IMG

decreased circulating total protein level ( J:211773 )

IMPC - CCP-IMG

immune system

abnormal thymus morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

♀

IMPC - CCP-IMG

decreased CD8-positive, naive alpha-beta T cell number ( J:211773 )

♂

IMPC - CCP-IMG

decreased effector memory T-helper cell number ( J:211773 )

IMPC - CCP-IMG

increased leukocyte cell number ( J:211773 )

♂

IMPC - CCP-IMG

increased eosinophil cell number ( J:211773 )

♂

IMPC - CCP-IMG

increased lymphocyte cell number ( J:211773 )

♂

IMPC - CCP-IMG

increased CD4-positive, alpha-beta T cell number ( J:211773 )

IMPC - CCP-IMG

increased T-helper cell number ( J:211773 )

IMPC - CCP-IMG

decreased spleen weight ( J:211773 )

IMPC - CCP-IMG

integument

abnormal skin morphology ( J:211773 )

IMPC - CCP-IMG

respiratory system

increased lung elastance ( J:211773 )

♂

IMPC - CCP-IMG

abnormal inspiratory capacity ( J:211773 )

♂

IMPC - CCP-IMG

decreased lung compliance ( J:211773 )

♂

IMPC - CCP-IMG

skeleton

abnormal tooth morphology ( J:211773 )

♂

IMPC - CCP-IMG