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Phenotypes Associated with This Genotype
Genotype
MGI:7388201
Allelic
Composition
Crotem1Akw/Crotem1Akw
Ldlrtm1Her/Ldlrtm1Her
Genetic
Background
B6.Cg-Crotem1Akw Ldlrtm1Her
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crotem1Akw mutation (0 available); any Crot mutation (46 available)
Ldlrtm1Her mutation (21 available); any Ldlr mutation (78 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• mice fed a high-fat diet exhibit attenuated calcification of the aortic and carotid arteries compared with control mice
• reduced macrophage accumulation in mice fed a high-fat diet

immune system
• reduced macrophage accumulation in mice fed a high-fat diet

skeleton
N
• mice exhibit normal bone density


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/31/2026
MGI 6.24
The Jackson Laboratory