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Phenotypes Associated with This Genotype
Genotype
MGI:7339121
Allelic
Composition
Fgfr1tm1Jpa/Fgfr1tm1Jpa
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgfr1tm1Jpa mutation (0 available); any Fgfr1 mutation (219 available)
Gt(ROSA)26Sortm1Sor mutation (10 available); any Gt(ROSA)26Sor mutation (1062 available)
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• maxillary processes are slightly reduced at E10.5
• frontonasal prominence is slightly reduced at E10.5
• cranial neural crest (CNC) cell participation in the frontonasal prominence is markedly reduced
• however, neural tube formation is normal

digestive/alimentary system
• maxillary processes are slightly reduced at E10.5

growth/size/body
• maxillary processes are slightly reduced at E10.5

skeleton
• maxillary processes are slightly reduced at E10.5


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory