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Phenotypes Associated with This Genotype
Genotype
MGI:7312058
Allelic
Composition		 Sh3rf1em1Bcgen/Sh3rf1em1Bcgen
Tg(Nes-cre)1Kln/0
Tg(Thy1-EGFP)MJrs/0
Genetic
Background		 involves: C57BL/6 * CBA * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sh3rf1em1Bcgen mutation (0 available); any Sh3rf1 mutation (54 available)
Tg(Nes-cre)1Kln mutation (4 available)
Tg(Thy1-EGFP)MJrs mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased dendritic spine density ( J:326378 )
• reduction in the number and volume of mushroom, thin, and filopodium spines
• however, stubby spine numbers are normal
decreased dendritic spine length ( J:326378 )
• with reduced complexity

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory