Phenotypes Associated with This Genotype

Genotype
MGI:7277816

• Allelic Composition: Prmt5^{tm2c(EUCOMM)Wtsi}/Prmt5^{tm2c(EUCOMM)Wtsi}; Tg(Col2a1/Acan-rtTA,tetO-cre)#Vlf/0
• Genetic Background: involves: C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

skeleton phenotype ( J:283043 )

N • no signs of scoliosis are seen following induction of recombinase expression at either 2 or 4 weeks of age

abnormal intervertebral disk morphology ( J:283043 )

• at 4 months of age, 3 months post induction of recombinase expression, there is a minor increase in acellular clefts at the midline of the endplate

• however, no gross signs of degenerative histopathology are seen