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Phenotypes Associated with This Genotype
Genotype
MGI:6771723
Allelic
Composition
Nbntm2Zqw/Nbntm2Zqw
Tg(VAV1-cre)1Graf/0
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nbntm2Zqw mutation (0 available); any Nbn mutation (59 available)
Tg(VAV1-cre)1Graf mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• postnatal lethality due to lack of bone marrow development (J:251434)
• mice succumb at approximately 2 weeks of age to severe anemia (J:277750)

immune system
• large decrease in white blood cell count in 12-day-old mice
• mice exhibit lack of bone marrow development

hematopoietic system
• severe anemia
• large decrease in red blood cell count in 12-day-old mice
• large decrease in white blood cell count in 12-day-old mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory