About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:6764552
Allelic
Composition		 Apctm1Rak/Apc+
Pms2tm1.1Sks/Pms2tm1.1Sks
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm1Rak mutation (0 available); any Apc mutation (151 available)
Pms2tm1.1Sks mutation (0 available); any Pms2 mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
intestine polyps ( J:310354 )
• mice exhibit increased intestinal polyp formation with microsatellite instability compared with Apctm1Rak heterozygotes
• however, morphology of polyps is the same as in Apctm1Rak heterozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory