Phenotypes Associated with This Genotype

Genotype
MGI:6731378

• Allelic Composition: Mettl5^{em1(IMPC)Hmgu}/Mettl5^{em1(IMPC)Hmgu}
• Genetic Background: C57BL/6N-Mettl5^{em1(IMPC)Hmgu}/Ieg

Data Sources

IMPC Data for Mettl5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal behavior ( J:211773 )

♂

IMPC - HMGU

decreased anxiety-related response ( J:211773 )

♂

IMPC - HMGU

decreased thigmotaxis ( J:211773 )

♂

IMPC - HMGU

impaired pupillary reflex ( J:211773 )

♂

IMPC - HMGU

increased grip strength ( J:211773 )

♂

IMPC - HMGU

decreased vertical activity ( J:211773 )

♂

IMPC - HMGU

decreased locomotor activity ( J:211773 )

♂

IMPC - HMGU

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

craniofacial

abnormal cranium morphology ( J:211773 )

IMPC - HMGU

growth/size/body

abnormal head morphology ( J:211773 )

IMPC - HMGU

decreased body length ( J:211773 )

♂

IMPC - HMGU

increased spleen weight ( J:211773 )

♂

IMPC - HMGU

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - HMGU

hematopoietic system

increased spleen weight ( J:211773 )

♂

IMPC - HMGU

decreased erythrocyte cell number ( J:211773 )

♂

IMPC - HMGU

decreased hematocrit ( J:211773 )

♂

IMPC - HMGU

decreased hemoglobin content ( J:211773 )

♂

IMPC - HMGU

immune system

increased spleen weight ( J:211773 )

♂

IMPC - HMGU

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HMGU

nervous system

abnormal optic disk morphology ( J:211773 )

♂

IMPC - HMGU

skeleton

abnormal cranium morphology ( J:211773 )

IMPC - HMGU

vision/eye

impaired pupillary reflex ( J:211773 )

♂

IMPC - HMGU

abnormal optic disk morphology ( J:211773 )

♂

IMPC - HMGU

abnormal iris morphology ( J:211773 )

♂

IMPC - HMGU

iris synechia ( J:211773 )

♂

IMPC - HMGU

abnormal cornea morphology ( J:211773 )

IMPC - HMGU

abnormal lens morphology ( J:211773 )

♂

IMPC - HMGU

cataract ( J:211773 )

♂

IMPC - HMGU

abnormal retina morphology ( J:211773 )

♂

IMPC - HMGU

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal vitreous body morphology ( J:211773 )

IMPC - HMGU

persistence of hyaloid vascular system ( J:211773 )

IMPC - HMGU