Analysis Tools
cardiovascular system
digestive/alimentary system
immune system
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• large pannus tissue invasion in synovial joints in surviving mice at age P20
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• deformed ankles and wrists in surviving mice from age P7
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mortality/aging
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• surviving mice die by age 33 days
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• 80% of embryos die within hours of birth
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respiratory system
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• failure to initiate respiration: underinflated lungs in pups that died within hours of birth
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skeleton
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• large pannus tissue invasion in synovial joints in surviving mice at age P20
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• deformed ankles and wrists in surviving mice from age P7
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