Phenotypes Associated with This Genotype

Genotype
MGI:6724059

• Allelic Composition: Dcaf8^em1Rbren/Dcaf8^em1Rbren
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased copulatory plug deposition ( J:307635 )

♂ • reduced frequency of copulation plugs compared to wild type control

cellular

abnormal sperm head morphology ( J:307635 )

♂ • more than 40% of spermatids show bent head malformations

decreased sperm progressive motility ( J:307635 )

♂ • progressive motility, path velocity (VAP), progressive velocity (VSL), and track speed (VCL) were significantly lower

reproductive system

abnormal sperm head morphology ( J:307635 )

♂ • more than 40% of spermatids show bent head malformations

decreased sperm progressive motility ( J:307635 )

♂ • progressive motility, path velocity (VAP), progressive velocity (VSL), and track speed (VCL) were significantly lower

reduced male fertility ( J:307635 )

♂ • in addition to reduced male fertility by mating, the homozygous male showed the severely reduced in vitro fertilization rates