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Phenotypes Associated with This Genotype
Genotype
MGI:6720819
Allelic
Composition		 Crls1tm1Geno/Crls1tm1Geno
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crls1tm1Geno mutation (0 available); any Crls1 mutation (16 available)
Gt(ROSA)26Sortm1(cre/ERT2)Tyj mutation (7 available); any Gt(ROSA)26Sor mutation (1095 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased oxygen consumption ( J:266083 )
• primary brown adipocytes from tamoxifen-treated mice show a significant reduction in norepinephrine (NE)-induced uncoupled respiration relative to control cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory