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Phenotypes Associated with This Genotype
Genotype
MGI:6711716
Allelic
Composition		 Pde1aem1Cjwa/Pde1aem1Cjwa
Pkd2tm1Som/Pkd2tm2Som
Genetic
Background		 involves: 129 * C57BL/6J * C57BL/6N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pde1aem1Cjwa mutation (0 available); any Pde1a mutation (31 available)
Pkd2tm1Som mutation (0 available); any Pkd2 mutation (85 available)
Pkd2tm2Som mutation (0 available); any Pkd2 mutation (85 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
kidney cyst ( J:246596 )
• administration of desmopressin aggravates the renal cystic disease seen in Pkd2tm1Som/Pkd2tm2Som mice

growth/size/body
kidney cyst ( J:246596 )
• administration of desmopressin aggravates the renal cystic disease seen in Pkd2tm1Som/Pkd2tm2Som mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory