Analysis Tools
immune system
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• in the spleen, blood, and liver
• mice infected with murine cytomegalovirus exhibit reduced total and Ly49H+ after 1.5 days infection and milder after 3.5 days compared with control mice
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• decreased survival in vivo and in culture
• treatment with IL2-anti-IL2 complexes partially rescues the ability to reject B2m-deficient splenocytes
• slightly less granzyme A production in uninfected mice
• however, cells exhibit normal cell-mediated immunity when cultured with RMA-S and RMA-H60 target cells
• however, increased IL2 or IL15 amounts restores NK cell survival in culture
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• mice infected with murine cytomegalovirus exhibit reduced total and Ly49H+ after 1.5 days infection and milder after 3.5 days with reduced granzyme B production and higher viral loads early after infection in the spleen and lungs compared with control mice
• however, IFNG production from NK cells of cytomegalovirus virus-infected mice
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hematopoietic system
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• in the spleen, blood, and liver
• mice infected with murine cytomegalovirus exhibit reduced total and Ly49H+ after 1.5 days infection and milder after 3.5 days compared with control mice
|
|
• decreased survival in vivo and in culture
• treatment with IL2-anti-IL2 complexes partially rescues the ability to reject B2m-deficient splenocytes
• slightly less granzyme A production in uninfected mice
• however, cells exhibit normal cell-mediated immunity when cultured with RMA-S and RMA-H60 target cells
• however, increased IL2 or IL15 amounts restores NK cell survival in culture
|
