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Phenotypes Associated with This Genotype
Genotype
MGI:6489855
Allelic
Composition		 Fan1em1Mem/Fan1em1Mem
Genetic
Background		 C57BL/6J-Fan1em1Mem
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fan1em1Mem mutation (0 available); any Fan1 mutation (98 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell nucleus morphology ( J:298297 )
• karyomegaly in the kidney at 5 months
increased cellular sensitivity to alkylating agents ( J:298297 )
• in response to mitomycin C in embryonic fibroblasts

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory