Phenotypes Associated with This Genotype

Genotype
MGI:6461761

• Allelic Composition: Tnks^{em1(IMPC)Hmgu}/Tnks^{em1(IMPC)Hmgu}
• Genetic Background: C57BL/6N-Tnks^{em1(IMPC)Hmgu}/Ieg

Data Sources

IMPC Data for Tnks

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

IMPC - HMGU

behavior/neurological

decreased grip strength ( J:211773 )

♀

IMPC - HMGU

decreased vertical activity ( J:211773 )

♂

IMPC - HMGU

cardiovascular system

increased heart weight ( J:211773 )

IMPC - HMGU

growth/size/body

increased heart weight ( J:211773 )

IMPC - HMGU

increased lean body mass ( J:211773 )

♀

IMPC - HMGU

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

IMPC - HMGU

increased red blood cell distribution width ( J:211773 )

IMPC - HMGU

thrombocytopenia ( J:211773 )

IMPC - HMGU

increased mean platelet volume ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

IMPC - HMGU

increased fasting circulating glucose level ( J:211773 )

IMPC - HMGU

decreased circulating glucose level ( J:211773 )

♀

IMPC - HMGU

decreased circulating cholesterol level ( J:211773 )

♀

IMPC - HMGU

decreased circulating HDL cholesterol level ( J:211773 )

♀

IMPC - HMGU

decreased circulating triglyceride level ( J:211773 )

IMPC - HMGU

increased circulating alkaline phosphatase level ( J:211773 )

♂

IMPC - HMGU

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - HMGU

nervous system

hydrocephaly ( J:211773 )

♂

IMPC - HMGU

skeleton

abnormal vertebrae morphology ( J:211773 )

IMPC - HMGU

abnormal bone structure ( J:211773 )

♀

IMPC - HMGU

decreased bone mineral content ( J:211773 )

IMPC - HMGU

decreased bone mineral density ( J:211773 )

IMPC - HMGU

vision/eye

abnormal retina morphology ( J:211773 )

♂

IMPC - HMGU

decreased total retina thickness ( J:211773 )

♂

IMPC - HMGU