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Phenotypes Associated with This Genotype
Genotype
MGI:6452104
Allelic
Composition		 Pld4tm1.2Nemz/Pld4tm1.2Nemz
Rag1tm1Mom/Rag1tm1Mom
Genetic
Background		 involves: 129 * 129S7/SvEvBrd * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pld4tm1.2Nemz mutation (0 available); any Pld4 mutation (26 available)
Rag1tm1Mom mutation (56 available); any Rag1 mutation (132 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal peritoneal macrophage morphology ( J:281205 )
• elevated expression of major histocompatibility complex (MHC) class II peptides on surface of resident peritoneal macrophages

immune system
abnormal peritoneal macrophage morphology ( J:281205 )
• elevated expression of major histocompatibility complex (MHC) class II peptides on surface of resident peritoneal macrophages

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory