Phenotypes for Ldlr Pla2g12a MGI:6448103 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ldlr^tm1Her/Ldlr^tm1Her Pla2g12a^rs36523879-C/Pla2g12a^rs36523879-C
Genetic Background	FVB.Cg-Pla2g12a^rs36523879-C Ldlr^tm1Her

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ldlr^tm1Her mutation (21 available); any Ldlr mutation (78 available)
Pla2g12a^rs36523879-C mutation (0 available); any Pla2g12a mutation (12 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

increased susceptibility to diet-induced aortic fatty streak lesions ( J:290574 )

• 2.5-fold larger lesions than in control mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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