Phenotypes Associated with This Genotype

Genotype
MGI:6402594

• Allelic Composition: Nmi^tm1.1Geno/Nmi^tm1.1Geno; Tg(KRT14-cre)1Amc/0; Tg(MMTVneu)202Mul/0
• Genetic Background: involves: 129S/SvEv * C57BL/6 * CBA * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

increased mammary adenocarcinoma incidence ( J:261035 )

• shorter latency to tumor formation

• accelerated tumor growth

• higher metastasis incidence

integument

increased mammary adenocarcinoma incidence ( J:261035 )

• shorter latency to tumor formation

• accelerated tumor growth

• higher metastasis incidence

neoplasm

increased mammary adenocarcinoma incidence ( J:261035 )

• shorter latency to tumor formation

• accelerated tumor growth

• higher metastasis incidence

increased metastatic potential ( J:261035 )

• increased pulmonary metastasis by mammary tumors