Phenotypes Associated with This Genotype

Genotype
MGI:6377096

• Allelic Composition: Marveld1^tm1.1Liy/Marveld1^tm1.1Liy; Tg(GFAP-cre)25Mes/0
• Genetic Background: involves: C57BL/6J * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal CNS glial cell morphology ( J:279065 )

• absence of strong glial fibers in mice at 6 days of age

abnormal cerebellar granule cell migration ( J:279065 )

• granule cells accumulate on the molecular layer

abnormal cerebellar Purkinje cell layer ( J:279065 )

• irregular at 6 days of age

abnormal Purkinje cell dendrite morphology ( J:279065 )

• apical dendritic arbors are abnormal and unable to anchor in the basement membrane

cellular

abnormal CNS glial cell morphology ( J:279065 )

• absence of strong glial fibers in mice at 6 days of age

abnormal cerebellar granule cell migration ( J:279065 )

• granule cells accumulate on the molecular layer