About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:6369064
Allelic
Composition
Plet1em1Yhh/Plet1em1Yhh
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plet1em1Yhh mutation (0 available); any Plet1 mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• substantially reduced tumor numbers in the AOM/DSS colon cancer model

digestive/alimentary system
• significantly increased gut permiability

homeostasis/metabolism
• impaired tissue repair of DSS-induced damage in colon epithelium


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory