Phenotypes for Ighg1 Mir146 MGI:6360061 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mir146^tm1.1Lfl/Mir146^tm1.1Lfl Ighg1^tm1(cre)Cgn/Ighg1⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ighg1^tm1(cre)Cgn mutation (4 available); any Ighg1 mutation (30 available)
Mir146^tm1.1Lfl mutation (1 available); any Mir146 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased germinal center B cell number ( J:266124 )

• mild day 28 post immunization with sheep red blood cells

increased T follicular helper cell number ( J:266124 )

• mild day 28 post immunization with sheep red blood cells

hematopoietic system

increased germinal center B cell number ( J:266124 )

• mild day 28 post immunization with sheep red blood cells

increased T follicular helper cell number ( J:266124 )

• mild day 28 post immunization with sheep red blood cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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